Exposure to well water and pesticides in Parkinson's disease: A case‐control study in the madrid area
Identifieur interne : 006022 ( Main/Exploration ); précédent : 006021; suivant : 006023Exposure to well water and pesticides in Parkinson's disease: A case‐control study in the madrid area
Auteurs : Félix Javier Jiménez-Jiménez [Espagne] ; Dolores Mateo [Espagne] ; Santiago Giménez-Roldán [Espagne]Source :
- Movement Disorders [ 0885-3185 ] ; 1992.
Descripteurs français
- Wicri :
- geographic : Espagne.
- topic : épidémiologie.
English descriptors
- KwdEn :
- Aged, Epidemiology, Etiology, Female, Humans, Male, Middle Aged, Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (diagnosis), Parkinson's disease, Pesticide Residues (adverse effects), Pesticide Residues (analysis), Pesticides, Risk Factors, Rural Population, Spain, Water Pollutants, Chemical (administration & dosage), Water Pollutants, Chemical (adverse effects), Water Supply (analysis), Well water exposure.
- MESH :
- chemical , administration & dosage : Water Pollutants, Chemical.
- chemical , adverse effects : Pesticide Residues, Water Pollutants, Chemical.
- chemical , analysis : Pesticide Residues.
- geographic : Spain.
- analysis : Water Supply.
- chemically induced : Parkinson Disease, Secondary.
- diagnosis : Parkinson Disease, Secondary.
- Aged, Female, Humans, Male, Middle Aged, Risk Factors, Rural Population.
Abstract
Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex‐matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p < 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future casecontrol studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed.
Url:
DOI: 10.1002/mds.870070209
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1992">1992</date><biblScope unit="vol">7</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="149">149</biblScope><biblScope unit="page" to="152">152</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">2387DE501581F7E4E353C49A349D7C11FC629787</idno><idno type="DOI">10.1002/mds.870070209</idno><idno type="ArticleID">MDS870070209</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Epidemiology</term><term>Etiology</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease, Secondary (chemically induced)</term><term>Parkinson Disease, Secondary (diagnosis)</term><term>Parkinson's disease</term><term>Pesticide Residues (adverse effects)</term><term>Pesticide Residues (analysis)</term><term>Pesticides</term><term>Risk Factors</term><term>Rural Population</term><term>Spain</term><term>Water Pollutants, Chemical (administration & dosage)</term><term>Water Pollutants, Chemical (adverse effects)</term><term>Water Supply (analysis)</term><term>Well water exposure</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Water Pollutants, Chemical</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Pesticide Residues</term><term>Water Pollutants, Chemical</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Pesticide Residues</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Spain</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>épidémiologie</term></keywords><keywords scheme="MESH" qualifier="analysis" xml:lang="en"><term>Water Supply</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Risk Factors</term><term>Rural Population</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex‐matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p < 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future casecontrol studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed.</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Jimenez Imenez, Felix Javier" sort="Jimenez Imenez, Felix Javier" uniqKey="Jimenez Imenez F" first="Félix Javier" last="Jiménez-Jiménez">Félix Javier Jiménez-Jiménez</name></region><name sortKey="Gimenez Oldan, Santiago" sort="Gimenez Oldan, Santiago" uniqKey="Gimenez Oldan S" first="Santiago" last="Giménez-Roldán">Santiago Giménez-Roldán</name><name sortKey="Jimenez Imenez, Felix Javier" sort="Jimenez Imenez, Felix Javier" uniqKey="Jimenez Imenez F" first="Félix Javier" last="Jiménez-Jiménez">Félix Javier Jiménez-Jiménez</name><name sortKey="Mateo, Dolores" sort="Mateo, Dolores" uniqKey="Mateo D" first="Dolores" last="Mateo">Dolores Mateo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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